{"id":3363,"date":"2021-02-19T07:27:28","date_gmt":"2021-02-19T07:27:28","guid":{"rendered":"https:\/\/www.iasoivf.com\/?p=3363"},"modified":"2021-02-19T07:39:24","modified_gmt":"2021-02-19T07:39:24","slug":"%cf%80%cf%81%ce%bf%ce%b5%ce%bc%cf%86%cf%85%cf%84%ce%b5%cf%85%cf%84%ce%b9%ce%ba%cf%8c%cf%82-%ce%b3%ce%b5%ce%bd%ce%b5%cf%84%ce%b9%ce%ba%cf%8c%cf%82-%ce%ad%ce%bb%ce%b5%ce%b3%cf%87%ce%bf%cf%82-pgt","status":"publish","type":"post","link":"https:\/\/www.iasoivf.com\/el\/%cf%80%cf%81%ce%bf%ce%b5%ce%bc%cf%86%cf%85%cf%84%ce%b5%cf%85%cf%84%ce%b9%ce%ba%cf%8c%cf%82-%ce%b3%ce%b5%ce%bd%ce%b5%cf%84%ce%b9%ce%ba%cf%8c%cf%82-%ce%ad%ce%bb%ce%b5%ce%b3%cf%87%ce%bf%cf%82-pgt\/","title":{"rendered":"\u03a0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 (PGT) \u03ba\u03b1\u03b9 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 (IVF)"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: left top;background-repeat: no-repeat;padding-top:100px;padding-right:0px;padding-bottom:70px;padding-left:0px;margin-bottom: 0px;margin-top: 60px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:30px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;background-color:#ffffff;border-width: 0px 0px 0px 0px;border-color:#dddddd;border-style:solid;padding: 0px 40px 0px 40px;\"><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-three\" style=\"margin-top:0px;margin-bottom:30px;\"><h3 class=\"title-heading-left\" style=\"margin:0;\"><p style=\"text-align: left;\">\u03a0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 (PGT) \u03ba\u03b1\u03b9 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 (IVF)<\/p><\/h3><\/div><div class=\"fusion-text fusion-text-1\"><p>\u039f\u039f\u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 (PGT) \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b5\u03c0\u03b5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 (IVF). \u0393\u03b9\u03b1 \u03bd\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b7 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7, \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf \u03bd\u03b1 \u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03ae\u03c3\u03bf\u03c5\u03bd \u03b4\u03cd\u03bf \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03bc\u03b2\u03c1\u03c5\u03bf\u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac. \u03a4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03c6\u03b1\u03af\u03c1\u03b5\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03ae \u03bc\u03b5\u03c1\u03b9\u03ba\u03ce\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd, \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ac \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5, \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03bf \u03c4\u03b7 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03ae \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd.<\/p>\n<p>\u0397 \u03b9\u03b4\u03ad\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03bc\u03cc\u03bd\u03c9\u03c3\u03b7 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03ad\u03bc\u03b2\u03c1\u03c5\u03bf \u03bc\u03b5 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b7 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c5\u03bb\u03b9\u03ba\u03bf\u03cd \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd \u03c0\u03b9\u03c3\u03c4\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 Gardner \u03ba\u03b1\u03b9 Edwards. \u039f\u03b9 \u03b4\u03cd\u03bf \u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03bf\u03bd\u03b5\u03c2 \u03ba\u03b1\u03c4\u03ac\u03c6\u03b5\u03c1\u03b1\u03bd \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03af\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf \u03c6\u03cd\u03bb\u03bf \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03ba\u03bf\u03c5\u03bd\u03b5\u03bb\u03b9\u03bf\u03cd \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03b1\u03c0\u03cc \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03c3\u03c4\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03c4\u03b7\u03c2 \u03b2\u03bb\u03b1\u03c3\u03c4\u03bf\u03ba\u03cd\u03c3\u03c4\u03b7\u03c2. \u03a3\u03c4\u03b1 \u03bc\u03ad\u03c3\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03b5\u03ba\u03b1\u03b5\u03c4\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 1980 \u03c4\u03cc\u03c3\u03bf \u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c0\u03bf\u03bc\u03cc\u03bd\u03c9\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 DNA \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 DNA \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03b1\u03bb\u03c5\u03c3\u03b9\u03b4\u03c9\u03c4\u03ae\u03c2 \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03bf\u03bb\u03c5\u03bc\u03b5\u03c1\u03ac\u03c3\u03b7\u03c2 (PCR &#8211; Polymerase Chain Reaction) \u03ac\u03bd\u03bf\u03b9\u03be\u03b5 \u03c4\u03b7\u03bd \u03c0\u03cc\u03c1\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03bao\u03cd \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 (PGT) \u03c3\u03c4\u03bf\u03bd \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf.<\/p>\n<p>\u0397 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2 (PGD &#8211; Preimplantation Genetic Diagnosis) \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c4\u03bf 1990 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03bf\u03c5 Handyside et al \u03b3\u03b9\u03b1 \u03c6\u03c5\u03bb\u03bf\u03c3\u03cd\u03bd\u03b4\u03b5\u03c4\u03bf \u03bd\u03cc\u03c3\u03b7\u03bc\u03b1. \u0397 \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03c4\u03c1\u03af\u03c4\u03b7\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b1\u03c2 \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 \u03ba\u03b1\u03b9, \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03b1\u03c0\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c6\u03cd\u03bb\u03bf \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5, \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03bc\u03b7\u03c4\u03c1\u03b9\u03ba\u03ae \u03ba\u03bf\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c4\u03c9\u03bd \u03b8\u03b7\u03bb\u03c5\u03ba\u03ce\u03bd-\u03c5\u03b3\u03b9\u03ce\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd.<\/p>\n<p>\u0391\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03c1\u03bf\u03ad\u03ba\u03c5\u03c8\u03b1\u03bd \u03bf\u03b9 \u03c0\u03c1\u03ce\u03c4\u03b5\u03c2 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03c5\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf. \u0395\u03ba\u03c4\u03cc\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03bc\u03bf\u03bd\u03bf\u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ce\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03c4\u03b1 \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1, \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c7\u03b8\u03b7\u03ba\u03b5 \u03c0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03b7 \u03b1\u03bd\u03c4\u03af\u03bb\u03b7\u03c8\u03b7 \u03cc\u03c4\u03b9 \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 (PGS &#8211; Preimplantation Genetic Screening). \u0397 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03b5\u03c5\u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03b8\u03b1 \u03bc\u03b5\u03af\u03c9\u03bd\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c0\u03bf\u03b2\u03bf\u03bb\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c8\u03c5\u03c7\u03b9\u03ba\u03bf\u03cd stress \u03b1\u03c0\u03cc \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b5\u03c2 \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2.<\/p>\n<p>\u0397 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae FISH (Fluorescense In Situ Hybridization) \u03ad\u03b4\u03c9\u03c3\u03b5 \u03c4\u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c1\u03b9\u03ba\u03ce\u03bd \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b5\u03c2, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c3\u03b5 \u03bc\u03b5\u03c4\u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03c7\u03b8\u03b7\u03ba\u03b5 \u03b7 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5 \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2. \u0397 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae \u03c4\u03b7\u03c2 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7\u03c2 \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 (WGA &#8211; Whole Genome Amplification) \u03b5\u03c5\u03bd\u03cc\u03b7\u03c3\u03b5 \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03bd\u03ad\u03c9\u03bd \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ce\u03bd \u03c5\u03c8\u03b7\u03bb\u03ae\u03c2 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03bf\u03bc\u03ae \u03c4\u03c9\u03bd \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd. \u039c\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c1\u03b9\u03b8\u03bc\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ce\u03bd \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03ce\u03bd \u03b1\u03bb\u03bb\u03b1\u03b3\u03ce\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c3\u03c5\u03c3\u03c4\u03bf\u03b9\u03c7\u03af\u03b5\u03c2 \u03c3\u03c5\u03b3\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03bf\u03cd \u03b3\u03b5\u03bd\u03c9\u03bc\u03b9\u03ba\u03bf\u03cd \u03c5\u03b2\u03c1\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd (array CGA) \u03ba\u03b1\u03b9 \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03cd\u03c7\u03b9\u03c3\u03b7 \u03bd\u03ad\u03b1\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ac\u03c2 (NGS).<\/p>\n<p>PGT \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03c5\u03c0\u03bf\u03b3\u03cc\u03bd\u03b9\u03bc\u03b1 \u03ae \u03bc\u03b7 \u03c5\u03c0\u03bf\u03b3\u03cc\u03bd\u03b9\u03bc\u03b1 \u03b6\u03b5\u03c5\u03b3\u03ac\u03c1\u03b9\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 \u03c6\u03c5\u03bb\u03bf\u03c3\u03cd\u03bd\u03b4\u03b5\u03c4\u03bf\u03c5 \u03ae \u03b1\u03c5\u03c4\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03bf\u03cd \u03bc\u03bf\u03bd\u03bf\u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03bf\u03cd \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 (PGT-M) \u03ae \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1\u03c2 \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03c9\u03bc\u03b1\u03bb\u03af\u03b1\u03c2 (PGT-SR). \u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03c3\u03c4\u03b5\u03af \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ce\u03bd \u03b1\u03c0\u03bf\u03b2\u03bf\u03bb\u03ce\u03bd \u03c0\u03c1\u03ce\u03c4\u03bf\u03c5 \u03c4\u03c1\u03b9\u03bc\u03ae\u03bd\u03bf\u03c5, \u03c3\u03b5 \u03b6\u03b5\u03c5\u03b3\u03ac\u03c1\u03b9\u03b1 \u03bc\u03b5 \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03bf\u03cd\u03c2 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03b7\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03ba\u03cd\u03ba\u03bb\u03bf\u03c5\u03c2 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b6\u03b5\u03c5\u03b3\u03ac\u03c1\u03b9\u03b1 \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03b7\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 (&gt;40 \u03ad\u03c4\u03b7) \u03b3\u03b9\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 (PGT-A).<\/p>\n<p>\u03a4\u03ad\u03bb\u03bf\u03c2, \u03bf \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03c3\u03c4\u03b5\u03af \u03b3\u03b9\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03b3\u03b9\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03cc\u03c8\u03b9\u03bc\u03b7\u03c2 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b1 \u03b9\u03c3\u03c4\u03bf\u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ac \u03bc\u03b5 \u03ae\u03b4\u03b7 \u03c0\u03ac\u03c3\u03c7\u03bf\u03bd \u03c0\u03b1\u03b9\u03b4\u03af (HLA-typing).<\/p>\n<p><strong>\u0395\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03c3\u03c4\u03b1\u03b4\u03af\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd <\/strong><\/p>\n<p>\u0397 \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03c3\u03c4\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03c4\u03bf\u03c5 \u03b6\u03c5\u03b3\u03ce\u03c4\u03b7, \u03c3\u03b5 \u03c4\u03c1\u03af\u03c4\u03b7\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b1\u03c2 \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 (\u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03b1\u03c5\u03bb\u03ac\u03ba\u03c9\u03c3\u03b7\u03c2) \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03ad\u03bc\u03c0\u03c4\u03b7\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b1\u03c2 \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 (\u03c3\u03c4\u03ac\u03b4\u03b9\u03bf 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\u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 DNA \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03c3\u03b5\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2 \u03c4\u03af\u03b8\u03b5\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03bc\u03c6\u03b9\u03c3\u03b2\u03ae\u03c4\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd.<\/p>\n<p><strong>\u03a0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf <\/strong><\/p>\n<p>\u039f PGT \u03b3\u03b9\u03b1 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03ba\u03bb\u03b7\u03c1\u03bf\u03bd\u03bf\u03bc\u03bf\u03cd\u03bc\u03b5\u03bd\u03c9\u03bd \u03bc\u03bf\u03bd\u03bf\u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ce\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ce\u03bd \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03ce\u03bd \u03b1\u03bd\u03c9\u03bc\u03b1\u03bb\u03b9\u03ce\u03bd \u03b1\u03bd\u03b5\u03be\u03b1\u03c1\u03c4\u03ae\u03c4\u03c9\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03c5\u03c0\u03bf\u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03bb\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae\u03c2 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03cd\u03b7\u03c3\u03b7\u03c2. \u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae \u0395\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1 \u0391\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b7\u03c2 \u0391\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 (ESHRE) \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03b3\u03bf\u03bd\u03b5\u03af\u03c2 \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ae \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03ae \u03b1\u03bd\u03c9\u03bc\u03b1\u03bb\u03af\u03b1 (PGT-SR), \u03ad\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03cc \u03bc\u03ad\u03c1\u03bf\u03c2 (~60%-65%) \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03cd\u03bd\u03bf\u03bb\u03bf \u03c4\u03c9\u03bd \u03c9\u03bf\u03bb\u03b7\u03c8\u03b9\u03ce\u03bd \u03b8\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bb\u03ae\u03be\u03b5\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5.<\/p>\n<p>\u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1, \u03b1\u03bd\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bc\u03b5 \u03ad\u03bd\u03b1 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03ba\u03cd\u03b7\u03c3\u03b7\u03c2 18% \u03b1\u03bd\u03ac \u03c9\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03ba\u03b1\u03b9 28% \u03b1\u03bd\u03ac \u03b5\u03bc\u03b2\u03c1\u03c5\u03bf\u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac. \u039d\u03bf\u03b5\u03af\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03b1\u03c0\u03bf\u03ba\u03bb\u03af\u03c3\u03b5\u03b9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b7\u03b8\u03bf\u03cd\u03bd \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c4\u03cd\u03c0\u03bf \u03c4\u03b7\u03c2 \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03c9\u03bc\u03b1\u03bb\u03af\u03b1\u03c2. \u03a3\u03b5 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03bc\u03bf\u03bd\u03bf\u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03bf\u03cd \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b1\u03c6\u03ce\u03c2 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1. \u03a0\u03b9\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03b1\u03bd\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bc\u03b5 \u03c3\u03b5 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc &gt;90% \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c5\u03c0\u03cc\u03ba\u03b5\u03b9\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bc\u03b5 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7, \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd. \u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03c4\u03bf 80% \u03ba\u03cd\u03ba\u03bb\u03c9\u03bd PGT-\u039c \u03b8\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bb\u03ae\u03be\u03bf\u03c5\u03bd \u03c3\u03b5 \u03b5\u03bc\u03b2\u03c1\u03c5\u03bf\u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03bc\u03b5 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 ~25% \u03b1\u03bd\u03ac \u03c9\u03bf\u03bb\u03b7\u03c8\u03af\u03b1 \u03ba\u03b1\u03b9 ~30% \u03b1\u03bd\u03ac \u03b5\u03bc\u03b2\u03c1\u03c5\u03bf\u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac.<\/p>\n<p>\u0397 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 (PGT-A) \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03b1\u03c0\u03cc \u03b2\u03b9\u03bf\u03c8\u03af\u03b1 \u03b2\u03bb\u03b1\u03c3\u03c4\u03bf\u03ba\u03cd\u03c3\u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c4\u03b7\u03bd \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae\u03c2 \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03c0\u03c1\u03bf\u03c2 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac. \u039c\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc \u03bd\u03b1 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bf\u03cd\u03bd \u03b5\u03c5\u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1, \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2. \u03a4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2 \u03b5\u03c5\u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 &gt;60%, \u03cc\u03c4\u03b1\u03bd \u03c4\u03bf \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03bb\u03ae \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 25%. \u03a3\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2, \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 45%-50% \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c5\u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac, \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03cc\u03bc\u03c9\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b1 \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2.<\/p>\n<p>\u0397 \u03b5\u03b9\u03c3\u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03b7\u03c2 \u03bc\u03b5\u03b8\u03cc\u03b4\u03bf\u03c5 \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03cd\u03c7\u03b9\u03c3\u03b7\u03c2 \u03bd\u03ad\u03b1\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ac\u03c2 (Next Generation Sequencing &#8211; NGS) \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03b1\u03c1\u03b9\u03b8\u03bc\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ce\u03bd \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03ce\u03bd \u03b1\u03bd\u03c9\u03bc\u03b1\u03bb\u03b9\u03ce\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03ce\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd. \u03a4\u03b1 \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03ac \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03bb\u03ac\u03b8\u03b7 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b9\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b5\u03c2 \u03bc\u03b9\u03c4\u03c9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03b9\u03c1\u03ad\u03c3\u03b5\u03b9\u03c2, \u03b5\u03bd\u03ce \u03b7 \u03c3\u03c5\u03bc\u03b2\u03bf\u03bb\u03ae \u03c4\u03c9\u03bd \u03bb\u03b1\u03b8\u03ce\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd \u03c3\u03c4\u03bf \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03c0\u03bf\u03af\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9. \u0398\u03b5\u03c9\u03c1\u03b7\u03c4\u03b9\u03ba\u03ac, \u03cc\u03c3\u03bf \u03c0\u03b9\u03bf \u03bd\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03bb\u03ac\u03b8\u03bf\u03c2 \u03c3\u03c4\u03bf\u03bd \u03ba\u03cd\u03ba\u03bb\u03bf \u03c4\u03c9\u03bd \u03bc\u03b9\u03c4\u03c9\u03c4\u03b9\u03ba\u03ce\u03bd \u03b4\u03b9\u03b1\u03b9\u03c1\u03ad\u03c3\u03b5\u03c9\u03bd \u03c4\u03bf\u03c5 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03c4\u03cc\u03c3\u03bf \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03bc\u03b2\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bc\u03ac \u03c4\u03bf\u03c5.<\/p>\n<p>\u0395\u03ac\u03bd \u03ad\u03bd\u03b1 \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03cc \u03ad\u03bc\u03b2\u03c1\u03c5\u03bf \u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03bf \u03b3\u03b9\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03ae \u03cc\u03c7\u03b9, \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c0\u03cc\u03c3\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03b9\u03b1 \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03b9\u03c3\u03bc\u03cc, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c4\u03b7\u03c2 \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2. \u0395\u03bd\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac, \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 20%-40% \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2 56%, \u03b5\u03bd\u03ce \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 \u03bc\u03b5 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc 40%- 80% \u03c3\u03b1\u03c6\u03ce\u03c2 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc 22%. \u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2, \u03b4\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b5\u03c1\u03b1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03b1 \u03b5\u03c5\u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1, \u03b5\u03bd\u03ce \u03c4\u03b1 \u03ad\u03bc\u03b2\u03c1\u03c5\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03cd \u03c1\u03af\u03c3\u03ba\u03bf\u03c5 \u03bc\u03c9\u03c3\u03b1\u03ca\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03bf \u03c7\u03c1\u03cc\u03bd\u03bf. \u0397 \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03b8\u03ad\u03bc\u03b1 \u03b4\u03c5\u03c3\u03c4\u03c5\u03c7\u03ce\u03c2 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03ba\u03c1\u03bf\u03c5\u03cc\u03bc\u03b5\u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1. \u0397 \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03bc\u03b5\u03bb\u03b5\u03c4\u03ce\u03bd \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u03b1\u03ba\u03ad\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03bb\u03ae\u03c2 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03b5\u03bd\u03ce \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03bd\u03ac \u03ba\u03cd\u03ba\u03bb\u03bf \u03b5\u03bc\u03b2\u03c1\u03c5\u03bf\u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 \u03b1\u03bd\u03c4\u03af \u03b3\u03b9\u03b1 \u03b1\u03c1\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf \u03ba\u03cd\u03ba\u03bb\u03bf \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2, \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03c0\u03b1\u03c1\u03b5\u03c1\u03bc\u03b7\u03bd\u03b5\u03af\u03b5\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd. \u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b5\u03bc\u03c6\u03cd\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2 \u03b5\u03c5\u03c0\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 100%, \u03b5\u03bd\u03ce \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c0\u03bf\u03b2\u03bf\u03bb\u03ce\u03bd \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03b1\u03c0\u03cc PGT-A \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 6%. \u0395\u03af\u03bd\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03b4\u03b5\u03ba\u03c4\u03cc \u03cc\u03c4\u03b9 \u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03b1\u03c5\u03c4\u03ae \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03b1\u03c0\u03cc\u03ba\u03c4\u03b7\u03c3\u03b7\u03c2 \u03c0\u03b1\u03b9\u03b4\u03b9\u03bf\u03cd, \u03c3\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c0\u03bf\u03bb\u03cd\u03b4\u03c5\u03bc\u03c9\u03bd \u03ba\u03c5\u03ae\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03b2\u03bf\u03bb\u03ce\u03bd \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7. \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b7 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03c4\u03cd\u03c7\u03b5\u03b9 \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03b1\u03b8\u03c1\u03bf\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03b1\u03bd\u03ac \u03b1\u03c1\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf \u03ba\u03cd\u03ba\u03bb\u03bf \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2, \u03b5\u03bd\u03ce \u03c0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1 \u03c4\u03bf \u03ba\u03cc\u03c3\u03c4\u03bf\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ac \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf.<\/p>\n<p>\u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03c5\u03b8\u03b5\u03af \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03b5 PGT-A \u03c3\u03b5 \u03c0\u03bf\u03bb\u03b9\u03ba\u03ac \u03c3\u03c9\u03bc\u03ac\u03c4\u03b9\u03b1 \u03c9\u03b1\u03c1\u03af\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03b7\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 (36-40), \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03b1\u03c5\u03c4\u03ae \u03b1\u03c0\u03ad\u03c4\u03c5\u03c7\u03b5 \u03bd\u03b1 \u03b1\u03c5\u03be\u03ae\u03c3\u03b5\u03b9 \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b6\u03ce\u03bd\u03c4\u03c9\u03bd \u03b3\u03b5\u03bd\u03bd\u03ae\u03c3\u03b5\u03c9\u03bd \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bb\u03b1\u03c3\u03b9\u03ba\u03ae \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b2\u03bf\u03ae\u03b8\u03b7\u03c3\u03b5 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03b2\u03bf\u03bb\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03ba\u03cd\u03ba\u03bb\u03c9\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2. \u03a4\u03ad\u03bb\u03bf\u03c2, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03b1\u03bd\u03b1\u03ba\u03bf\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u0391\u03bc\u03b5\u03c1\u03b9\u03ba\u03ac\u03bd\u03b9\u03ba\u03b7\u03c2 \u0388\u03bd\u03c9\u03c3\u03b7\u03c2 \u0391\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 (ASRM) \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03b1\u03c1\u03ba\u03ae \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03b2\u03b9\u03bf\u03c8\u03af\u03b1\u03c2 \u03b2\u03bb\u03b1\u03c3\u03c4\u03bf\u03ba\u03cd\u03c3\u03c4\u03b7\u03c2 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf \u03cc\u03bb\u03c9\u03bd \u03c4\u03c9\u03bd \u03c7\u03c1\u03c9\u03bc\u03bf\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03b5 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03c5\u03c0\u03bf\u03b3\u03cc\u03bd\u03b9\u03bc\u03b1 \u03b6\u03b5\u03c5\u03b3\u03ac\u03c1\u03b9\u03b1.<\/p>\n<p><strong><u>References<\/u><\/strong><\/p>\n<ol>\n<li>Gardner RL, Edwards RG. Control of the sex ratio at full term in the rabbit by transferring sexed blastocysts. Nature, 1968; 218: 346-349.<\/li>\n<li>Saiki RK, et al. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science, 1985; 230: 1.350-1.354.<\/li>\n<li>Li HH, et al. Amplification and analysis of DNA sequences in single human sperm and diploid cells. Nature, 1988; 335: 414-417.<\/li>\n<li>Handyside AH, et al. Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification. Nature, 1990; 344: 768-770.<\/li>\n<li>Wells D, et al. Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisation. Nucleic Acids Res, 1999; 27: 1.214-1.218.<\/li>\n<li>Fiorentino F., et al. Development and validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of embryos. Fertil Steril, 2014; 101: 1.375-1.382.<\/li>\n<li>Handyside AH. 24-chromosome copy number analysis: a comparison of available technologies. Fertil Steril, 2013; 100: 595-602.<\/li>\n<li>Scott RT Jr, et al. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertil Steril, 2013; 100: 624-630.<\/li>\n<li>Liu W, et al. Non-invasive pre-implantation aneuploidy screening and diagnosis of beta thalassemia IVSII654 mutation using spent embryo culture medium. Ann Med, 2017; 49: 319-328.<\/li>\n<li>Vera-Rodriguez M, et al. Origin and composition of cell-free DNA in spent medium from human embryo culture during preimplantation development. Hum Reprod, 2018; 33: 745-756.<\/li>\n<li>Hammond ER, Shelling AN, Cree LM. Nuclear and mitochondrial DNA in blastocoele fluid and embryo culture medium: evidence and potential clinical use. Hum Reprod, 2016; 31: 1.653-1.661.<\/li>\n<li>De Rycke M, et al. ESHRE PGD Consortium data collection XIV-XV: cycles from January 2011 to December 2012 with pregnancy follow-up to October 2013. Hum Reprod, 2017; 32: 1.974-1.994.<\/li>\n<li>Dahdouh EM, Balayla J, Garcia-Velasco JA. Comprehensive chromosome screening improves embryo selection: a meta-analysis. Fertil Steril, 2015; 104: 1.503-1.512.<\/li>\n<li>Munne S, et al. Detailed investigation into the cytogenetic constitution and pregnancy outcome of replacing mosaic blastocysts detected with the use of high-resolution next-generation sequencing. Fertil Steril, 2017; 108: 62-71 e8.<\/li>\n<li>Munne S, Wells D. Detection of mosaicism at blastocyst stage with the use of high-resolution next-generation sequencing. Fertil Steril, 2017; 107: 1.085-1.091.<\/li>\n<li>Verpoest W, et al. Preimplantation genetic testing for aneuploidy by microarray analysis of polar bodies in advanced maternal age: a randomized clinical trial. Hum Reprod, 2018; 33: 1.767-1.776.<\/li>\n<li>Practise Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology. The use of preimplantation genetic testing for aneuploidy (PGT-A): a committee opinion. Fertil Steril, 2018; 109: 429-436.<\/li>\n<\/ol>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-parallax-fixed nonhundred-percent-fullwidth non-hundred-percent-height-scrolling fusion-equal-height-columns\" style=\"background-color: rgba(255,255,255,0);background-image: url(&quot;http:\/\/www.iasoivf.com\/wp-content\/uploads\/2015\/12\/make-an-appointment.jpg&quot;);background-position: center center;background-repeat: no-repeat;padding-top:110px;padding-right:0px;padding-bottom:100px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;background-attachment:fixed;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_3_5 3_5 fusion-three-fifth fusion-column-first\" style=\"width:58.4%; margin-right: 4%;margin-top:0px;margin-bottom:30px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-2\"><h2 style=\"color: #ffffff; text-align: left;\">\u039a\u03bb\u03b5\u03af\u03c3\u03c4\u03b5 \u03c1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd<\/h2>\n<\/div><div class=\"fusion-text fusion-text-3\"><h3 style=\"color: #fcfcfc; text-align: left;\">\u03a0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03c4\u03b5 \u03c4\u03bf \u03c1\u03b1\u03bd\u03c4\u03b5\u03b2\u03bf\u03cd \u03c3\u03b1\u03c2 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1.<\/h3>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_2_5 2_5 fusion-two-fifth fusion-column-last\" style=\"width:37.6%;margin-top:0px;margin-bottom:30px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-column-content-centered\"><div class=\"fusion-column-content\"><div class=\"fusion-align-block\"><style type=\"text\/css\">.fusion-button.button-1 {border-radius:2px;}<\/style><a class=\"fusion-button button-flat button-xlarge button-default button-1 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"https:\/\/www.iasoivf.com\/el\/%CE%B5%CF%80%CE%B9%CE%BA%CE%BF%CE%B9%CE%BD%CF%89%CE%BD%CE%AF%CE%B1\/\"><span class=\"fusion-button-text\">\u0395\u03a0\u0399\u039a\u039f\u0399\u039d\u03a9\u039d\u0397\u03a3\u03a4\u0395 \u039c\u0391\u0396\u0399 \u039c\u0391\u03a3<\/span><\/a><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":3372,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[48],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u03a0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 IASO IVF Medical Center Cyprus<\/title>\n<meta name=\"description\" content=\"\u039f \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 (PGT) - \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 (IVF).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.iasoivf.com\/preimplantation-genetic-testing-pgt-and-ivf\/\" \/>\n<meta property=\"og:locale\" content=\"el_GR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u03a0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 IASO IVF Medical Center Cyprus\" \/>\n<meta property=\"og:description\" content=\"\u039f \u03c0\u03c1\u03bf\u03b5\u03bc\u03c6\u03c5\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 (PGT) - \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03cd\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 (IVF).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.iasoivf.com\/preimplantation-genetic-testing-pgt-and-ivf\/\" \/>\n<meta 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