The technique of assisted hatching is applied in some cases to help the embryo hatch from the protective zone surrounding it and attach to the womb. In the early stages of its development, the embryo is surrounded by a protective zone (zone pellucida).
In the later stages of development, the developing embryo should be released – hatched from this zone in order to be implanted in the uterus. Many times, embryos may not hatch because the zone is thick and hard to “break through”.
The purpose of this technique is to help the embryo “escape” from the zone by creating a small hole in it. This technique requires the use of a microscope and is usually performed with laser beams or an acid solution locally applied onto the zone with a special micropipette.
This technique is recommended in the following cases:
Like all other techniques, the technique of assisted hatching also involves risks, such as the possible destruction of an embryo. In particular cases, this technique can significantly increase the pregnancy expectation rate, while it is successfully applied in most IVF units.