Preimplantation Genetic Testing How, when and why is it done?
Preimplantation genetic testing (PGT) is inseparably linked to in vitro fertilisation and aims to control embryos that are grown in the laboratory. In other words, preimplantation testing is a test that allows us to analyse the DNA of the embryos before implanting them into the uterus. This test is performed when we want to detect possible chromosomal abnormalities in the foetuses (e.g. Down syndrome) or in cases of known and inherited diseases (e.g. Thalassaemia). To do this, a few cells, which are representative of the embryo of origin, are removed from it and then sent for molecular testing. If the cells of the fetus appear normal then this specific fetus is selected for transfer to the woman’s uterus.
This test is recommended for couples who are carriers or suffer from a genetic disease or in cases of multiple miscarriages, multiple failed attempts of in vitro fertilisation or for couples of increased reproductive age.
Confidence in scientists and laboratories with experience in both in vitro fertilisation and molecular analysis is a prerequisite for the success of the method.
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